Science behind metis Sleep 08

The science behind metis Sleep 08

EFFECTIVE SUPPLEMENTS? BROUGHT ECOLOGICALLY.

We strongly question current supplements. Skeptical we certainly are. A high concentration to sleep better? Check. Each formula has been perfected for maximum effect from the various ingredients. Thus, each capsule contains a decisive dose of natural, active substances.

metis Sleep 08 helps you fall asleep faster, sleep through and has a calming effect. This is a supplement on a natural basis and is not addictive. Keep fretting in bed? Don't fret.

Caffeine-free

Sugar-free

Vegan

No artificial colors

No synthetic preservatives

No artificial flavors or fragrances

Not addictive

Valerian and Eschscholzia

Valerian provides relief from mild nervous tension and sleep disorders. Thanks to its concentrated valerenic acid, it improves the quality of natural sleep.
Eschscholzia's exclusive alkaloids contribute to an anti-anxiety effect & improve restless sleep.
Valerian has a positive effect on:
Falling asleep
Falling asleep

Melatonin & Vitamin B6

Melatonin is the sleep hormone that makes you fall asleep.

Vitamin B6 supports the processing and effect of Valerian and eschscholzia and contributes to the production of melatonin.

References

Bent S, Padula A, Moore D, Patterson M, Mehling W. Valerian for sleep: a systematic review and meta-analysis. Am J Med. 2006; 119(12):1005-12.

Fedurco M, Gregorová J, Šebrlová K, Kantorová J, Peš O, Baur R, Sigel E, Táborská E. Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors. Biochem Res Int 2015; 2015:617620.

Journal of Traditional and Complementary Magazine, March 2019: A combination of Eschscholtzia californica Cham. and Valeriana officinalis L. Extracts for adjustments insomnia: A prospective observational study

"More in a capsule. More out of life."

Are you willing to give it your all? Then you will get more from us. Because in your hectic life, sometimes the bar is set high. How do you stay on top of your schedule? How do you start your day well-rested? metis offers you an effective dose of 'doing' and 'dreaming'. Replenish your nutrition and go full steam ahead.

Benefits and ingredients

We have carefully selected 4 natural ingredients, each with their own specific effect and benefits. metis Sleep 08 has three main benefits:

Helps with falling asleep

Fall asleep faster thanks to the effective combination of Melatonin and Valerian. Stop worrying and fall asleep carefree.

Helps to sleep through the night

Stay blissfully asleep for the rest of the night. Wake up wonderfully rested. Start the day full of energy.

Has a calming effect

Unwind completely with the calming properties of eschscholzia. De-stress and relax.

Valerian extract (0.8% valerenic acid)

Overview

Valerian is a well-known plant within phytotherapy. Extracts of this plant (obtained by extraction with water or 70% ethanol in water) can be effective for insomnia.

Effects

Valerian provides relief from mild nervous tension and sleep disorders. Thanks to the concentrated valerenic acid it improves the quality of natural sleep.

Benefits

Calming effect

Deeper sleep

Fall asleep faster

Learn more

References

1. Bent S, Padula A, Moore D, Patterson M, Mehling W. Valerian for sleep: a systematic review and meta-analysis. Am J Med. 2006; 119(12):1005-12.

Gharib M, Samani LN, Panah ZE, Naseri M, Bahrani N, Kiani K. The effect of valeric on anxiety severity in women undergoing hysterosalpingography. Glob J Health Sci 2015; 7(3):358-63.

Monograph. Valeriana officinalis. Altern Med Rev 2004; 9(4):438-41.

4. Pinheiro ML, Alcântara CE, de Moraes M, de Andrade ED. Valeriana officinalis L. for conscious sedation of patients submitted to impacted lower third molar surgery: A randomized, double-blind, placebo-controlled split-mouth study. J Pharm Bioallied Sci 2014; 6(2):109-14.

Valerian 5. Natural Medicines, Therapeutic Research Center 2017.

Eschscholzia californica (2% rutin)

Overview

The Sleeping Hat (Golden Poppy) is a flowering herb from North America. The plant is related to the Poppy and has beautiful flowers. It is also the flower of the State of California.

Effects

Like the Poppy, the plant and the small, black seeds of the fruit contain substances with mild sedative and analgesic effects. These substances, alkaloids, also help one sleep better.

Benefits

Helps with falling asleep

Helps with Stress

Reduces Anxiety

Reduces Pain

References

1. carlifornia poppy. Natural Medicines, Therapeutic Research Center 2015

3. Sarris J, McIntyre E, Camfield DA. Plant-based medicines for anxiety disorders, Part 1: a review of preclinical studies. CNS Drugs 2013; 27(3):207-19.

Active vitamin B6

Overview

Active vitamin B6, also known as Pyridoxal-5-phosphate, is a water-soluble vitamin that your body needs for a wide range of cognitive and physical functions.

Mechanism

Active vitamin B6 is a source of energy for brain cells, which is essential for proper brain function. Also causes the formation of the inhibitory neurotrasmitter GABA. This is then converted to seretonin.

Benefits

Supports energy metabolism

Supports brain function

Supports overall immune system health

References

1. Volpe AD, Lucia A, Pirozzi C, Pastore V. Comparative Study between the use of Melatonin and A Solution with Melatonin, Tryptophan, and Vitamin B6 as an Inducer of Spontaneous Sleep in Children During an Auditory Response Test: An Alternative to Commonly Used Sedative Drugs. J Int Adv Otol 2017; 13(1):69-73.

Vitamin B6. Natural Medicines, Therapeutic Research Center 2017.

Melatonin

Overview

Melatonin is a hormone that tells your body when it's time to go to sleep. It is produced by the pineal gland in the brain, but it is also found in other areas, such as the eyes, bone marrow, and intestines.

Mechanism

Melatonin regulates your sleep and determines your day and night rhythms. Light from a computer screen, smartphone, or television suppresses melatonin production and slows down your natural need for sleep. An unregulated biological clock reduces mental performance, alertness and has a negative impact on emotions. Taking melatonin right before bedtime supports and improves the start of a natural sleep pattern.

Benefits

Restores your biological clock

Can increase sleep efficiency and duration

References

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Why METIS®

Effective formulas by Pharmacist Dirk

Metis helps people like you tackle stress-related complaints such as poor sleep, lethargy and hair loss. Our unique formulas are formulated by Pharmacist Dirk, who uses his professional knowledge and personal experience to develop effective formulas. We use only natural, more absorbable substances and use only the best, most concentrated ingredients to ensure a tangible effect. Our formulas are available online and at more than 600 pharmacies and coaches in Belgium and the Netherlands. We are always ready to answer questions and provide personaliZed guidance.